These Chicken Alfredo Lasagna Roll-Ups are a rich and comforting twist on traditional lasagna. Tender lasagna noodles are filled with a creamy mixture of shredded chicken, ricotta, mozzarella, Parmesan, garlic, and fresh parsley, then topped with a homemade Alfredo sauce and baked until bubbly and golden.
Perfect for weeknight dinners or special family gatherings, this recipe delivers all the classic flavors of chicken Alfredo in an elegant, easy-to-serve presentation.
Who Is This Recipe For?
This recipe is perfect for:
- Families looking for a comforting homemade dinner
- Fans of creamy Alfredo pasta dishes
- Home cooks wanting a make-ahead meal
- Anyone with leftover cooked chicken to use
- Cheese lovers craving a rich baked pasta recipe
Why It’s Great
- Creamy homemade Alfredo sauce
- Packed with three delicious cheeses
- Great way to use leftover chicken
- Easy to prepare ahead of time
- Perfect for holidays, potlucks, or family dinners
- Freezer-friendly for meal prep
Recipe Overview
- Prep Time: 25 minutes
- Cook Time: 35–40 minutes
- Total Time: About 1 hour
- Servings: 4–6
Ingredients
Chicken & Cheese Filling
- ½ cup cooked shredded chicken
- 1¼ cups ricotta cheese
- ⅜ cup shredded mozzarella cheese
- ¼ cup grated Parmesan cheese
- 2 garlic cloves, minced
- 2 teaspoons fresh parsley, finely chopped
Homemade Alfredo Sauce
- 2 tablespoons butter
- 2 garlic cloves, minced
- 1 cup heavy cream
- ¾ cup grated Parmesan cheese
- Kosher salt and freshly ground black pepper, to taste
Assembly
- 8 cooked lasagna noodles, drained
- ½ cup shredded mozzarella cheese
- Fresh chopped parsley, for garnish
Instructions
1. Prepare the Filling
In a large mixing bowl, combine the shredded chicken, ricotta cheese, mozzarella, Parmesan, minced garlic, and parsley.
Mix until the filling is smooth, creamy, and evenly blended.
2. Make the Alfredo Sauce
Melt the butter in a saucepan over medium heat.
Add the minced garlic and cook for about 1 minute until fragrant.
Pour in the heavy cream and bring it to a gentle simmer, stirring frequently.
Gradually whisk in the Parmesan cheese until the sauce becomes smooth, creamy, and slightly thickened.
Season with salt and black pepper to taste, then remove from the heat.
3. Assemble the Roll-Ups
Lay each cooked lasagna noodle flat on a clean surface.
Spread an even layer of the chicken and cheese filling over each noodle.
Roll each noodle tightly from one end to the other.
4. Arrange in the Baking Dish
Spread a thin layer of Alfredo sauce over the bottom of a lightly greased baking dish.
Place the lasagna roll-ups seam-side down in the dish.
Pour the remaining Alfredo sauce evenly over the rolls.
Sprinkle the top with the remaining mozzarella cheese.
5. Bake
Preheat the oven to 375°F (190°C).
Bake uncovered for 30–35 minutes, or until the cheese is melted, bubbling, and lightly golden.
6. Garnish and Serve
Allow the roll-ups to rest for about 5 minutes before serving.
Finish with freshly chopped parsley for a bright, fresh touch.
Kitchen Equipment Needed
- Large mixing bowl
- Medium saucepan
- Whisk
- Measuring cups and spoons
- 9×13-inch baking dish
- Large pot for cooking noodles
- Spatula or spoon
Storage
Refrigerator
Store leftovers in an airtight container for up to 4 days.
Freezer
Freeze baked or unbaked roll-ups for up to 3 months. Thaw overnight in the refrigerator before reheating or baking.
Reheating
Warm in a 350°F (175°C) oven until heated through, or microwave individual portions for a quick meal.
FAQ
Can I use rotisserie chicken?
Yes. Rotisserie chicken is a convenient option and adds plenty of flavor.
Can I substitute cottage cheese for ricotta?
Absolutely. Cottage cheese can be used for a lighter filling with a slightly different texture.
Can I make this recipe ahead of time?
Yes. Assemble the roll-ups up to one day in advance, cover, refrigerate, and bake when ready.
What vegetables can I add?
Spinach, sautéed mushrooms, broccoli, or chopped sun-dried tomatoes all pair beautifully with the creamy Alfredo sauce.
Can I use store-bought Alfredo sauce?
Yes. Homemade Alfredo offers the freshest flavor, but a quality store-bought sauce works well when you’re short on time.
Conclusion
These Chicken Alfredo Lasagna Roll-Ups combine everything you love about creamy Alfredo pasta and classic lasagna into one irresistible dish. Filled with tender chicken, creamy ricotta, mozzarella, and Parmesan, then smothered in a rich homemade Alfredo sauce, they’re an elegant yet easy meal that’s perfect for both weeknight dinners and special occasions. One bite is all it takes to make this recipe a family favorite.
